To improve SLNB, whole-body imaging could improve detection and potentially prevent unnecessary surgery by identifying healthy and metastatic SLNs. It involves excision and histology of sentinel lymph nodes (SLNs) and presents two main challenges: (i) sensitive whole-body localisation of SLNs, and (ii) lack of pre-operative knowledge of their metastatic status, resulting in a high number (>70%) of healthy SLN excisions. Sentinel lymph node biopsy (SLNB) is commonly performed in cancers that metastasise via the lymphatic system. Select the file that you have just downloaded and select import option Reference Manager (RIS). 68Ga-Sienna+ for PET-MRI Guided Sentinel Lymph Node Biopsy: Synthesis and Preclinical Evaluation in a Metastatic Breast Cancer Model. Savolainen H, Volpe A, Phinikaridou A, Douek M, Fruhwirth G, de Rosales RTM. de Rosales, King's College London, St Thomas' Hospital, London SE1 7EH, United Kingdom, Tel: +44 (0)0, E-mail: London Centre for Nanotechnology, King's College London, Strand Campus, London, WC2R 2LS, United Kingdom (UK). Department of Research Oncology, School of Cancer & Pharmaceutical Sciences, King's College London, London, United KingdomĤ. Department of Biomedical Engineering, School of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdomģ. Department of Imaging Chemistry and Biology, School of Biomedical Engineering & Imaging Sciences, King's College London, London, United KingdomĢ. Heli Savolainen 1, Alessia Volpe 1, Alkystis Phinikaridou 2, Michael Douek 3, Gilbert Fruhwirth 1, Rafael T. Research Paper 68Ga-Sienna+ for PET-MRI Guided Sentinel Lymph Node Biopsy: Synthesis and Preclinical Evaluation in a Metastatic Breast Cancer Model
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